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Enzymatic's CoQ10 Maple 60mg 30Tabs

Enzymatic's CoQ10 Maple 60mg 30Tabs
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Why take CoQ10? You need it!

CoQ10 fuels the thousands of mitochondria responsible for your heart's energy production, helps maintain energy levels, and ensures sharp brain function.†



Why take Smart Q10™ CoQ10? It's the world's most clinically-studied CoQ10!***

The CoQ10 in this formula is clinically shown to support cardiac, neurological, and immune health.†

It is absorbed into both your bloodstream and cells.† The chewable tablet allows for immediate release and immediate benefits.†

It is CoQ10 in a pure, natural form - not synthesized:

CoQ10 can be synthesized, but that produces a distinctly different product with chemical compounds not found in the natural form. This supplement contains only the natural form of coenzyme Q10.

Directions Adults: Chew one tablet once or twice daily, or as directed by a healthcare practitioner. Children: As directed by a healthcare practitioner.

DESCRIPTION Smart Q10 CoQ10 wafers contain coenzyme Q10 emulsified in vitamin E and mixed tocopherols and is formulated with Micosolle®, a proprietary excipient.1 Clinical studies have demonstrated that this process enhances the absorption of CoQ10.2-4 Two different methods can be used for the production of coenzyme Q10. One method is natural and the other is synthetic. The natural process utilizes living organisms and is referred to as a “biological fermentation/extraction process.” Coenzyme Q10 can also be synthesized by a chemical process, which produces a similar, but distinctly different product that contains chemical compounds not found in the natural form. smart Q10 CoQ10 contains the natural form of coenzyme Q10.1

Smart Q10™ CoQ10:

The world's most clinically-studied CoQ10 in independent, peer-reviewed studies Cardiologist and Neurologist recommended for heart and brain health support† Made with all-natural vitamin E Available in 3 strength levels of support: 60 mg, 100 mg, and 200 mg

INTRODUCTION The Mitochondria Mitochondria are highly specialized structures (organelles) within each nucleated cell. The number of mitochondria in a cell depends on the cell's function. Cells with particularly heavy energy demands, such as heart muscle cells, have more mitochondria than other cells. The mitochondria's primary responsibility is to capture most of the energy in nutrients and convert it into cellular energy.9,10 This energy conversion and storage is a complex, multi-step process that follows a specific pathway. The converted cellular energy is stored in the energy-yielding molecule adenosine triphosphate (ATP) used to fuel the cell's activities. (This is similar to the energy stored in gasoline that is used to fuel automobiles). Because this process requires oxygen, it is often referred to as cellular respiration. Obtaining as many electrons out of the nutrients as possible is the goal of cellular respiration. That is why part of the pathway is referred to as the electron pathway chain.9,10 CoQ10 functions as a vital link in the process of converting nutrients into ATP. Cellular respiration and the electron transport chain are completely dependent on CoQ10.9,10

Mitochondrial Compartments Mitochondria are encased in double membranes. The smooth outer membrane encloses the periphery of the mitochondria and the inner membrane is enfolded to form the cristae. (Fig. 1) CoQ10 is found in the cristae folds. Cristae folds provide a large surface area for cellular respiration.9,10

Mitochondria are unusual organelles in that they contain their own deoxyribonucleic acid (DNA) and ribonucleic acid (RNA).9,10 Insufficient CoQ10 levels may have an effect on cellular respiration and mitochondrial DNA.6-8

Smart Q10™ CoQ10 and Support of Cardiac Health† Cardiac cells require large amounts of uninterrupted energy. They have a greater number of mitochondria and subsequently more CoQ10 than any other type of cell.10,11 Because of this association, CoQ10's support of cardiac health is well researched and documented.† CoQ10 supports healthy heart contractility and subsequent circulation, blood pressure, and exercise endurance.†6,11-15 Due to Smart Q10 CoQ10's ability to pass through the cell membrane and enter the mitochondria, enhanced levels can be attained.†2-4

Smart Q10™ CoQ10 and Support of the Neurological System † The Blood-Brain Barrier The blood-barrier is a unique anatomical structure. Simply stated, the cells that make up the blood vessels that provide blood to the brain are extremely close together. This greatly restricts what can and cannot leave the bloodstream and enter the brain. While the blood-brain barrier protects the brain from potentially toxic substances, it can be a significant obstacle to therapy of central nervous system disorders. In order to leave the bloodstream and reach the brain cells, a substance must be able to pass through the tightly connected cells of the capillary walls. (Fig. 2) Only substances with certain solubilities or those that have a transport system can cross the blood-brain barrier to a significant degree.16-18

Recently, CoQ10 has been studied for its effect in support of neurological health. When CoQ10 crosses the blood-brain barrier, mitochondrial concentrations are increased and clinical results indicate that significant neurosupportive effects follow.† Clinical studies have examined the role of CoQ10 in the neurological system.3,19-28

Smart Q10™ CoQ10 and Support of Immune Health† CoQ10 is necessary for immune health.† Increased free radical activity causes damage to cell membranes, mitochondria, and DNA. Supplementation with CoQ10 provides enhanced antioxidant activity that is supportive of the immune system.†4,7,29-34

Natural Vitamin E The common name “vitamin E” is an umbrella term for a family of compounds known as the tocopherols. There are at least 8 forms of tocopherols including, alpha-tocopherol, beta-tocopherol, delta-tocopherol, and gamma-tocopherol. These tocopherols are all naturally created by plants, and when used in vitamin E supplements, are considered natural vitamin E.35,36

Recently, the concomitant administration of vitamin E and CoQ10 has been studied. Research has demonstrated that CoQ10 can improve vitamin E's antioxidant function and protect it from depletion.†8,37-38

Smart Q10™ CoQ10 CoQ10 and Clinical Trials The formulation of Smart Q10™ CoQ10 is unique among CoQ10 supplements. Currently, three large multi-center studies investigating Smart Q10™ CoQ10 are ongoing. All of these clinical trials are investigating Smart Q10™ CoQ10 health supportive effects on the nervous system.†39-41 To date, 21 published studies have used Smart Q10™ CoQ10 in their research.42

HOW DOES IT WORK? CoQ10, also referred to as coenzyme Q 10 or ubiquinone, is a natural fat-soluble nutrient present in virtually all living cells in the body. CoQ10 has a crucial role as a cofactor in the mitochondrial synthesis of cellular energy.†5,6 Although it is produced by the body and exists in some dietary sources, these levels may be insufficient to meet the body's requirement. A deficiency can result from impaired synthesis due to nutritional deficiencies, increasing age, or increased tissue demands. Numerous diseases may exhibit CoQ10 depletion. CoQ10 also functions as a potent antioxidant.†6-8

However, all CoQ10 products are not equal. They vary greatly in quality and absorbability. Serum level determination of CoQ10 in the bloodstream is not necessarily the most important measure of efficacy.4 In order for it to be fully effective, it must cross the cellular barrier and raise the intracellular levels.† The only reliable indicator of CoQ10 supplementation is its presence in cell mitochondria.2 In central nervous system applications, CoQ10 must pass the blood brain barrier, resulting in increased brain intracellular levels to exert its effects.†3

Smart Q10™ CoQ10 is currently the only coenzyme Q10 supplement supported by studies that show increased serum levels, increased intracellular levels, and demonstrated ability to cross the blood brain barrier.†2-4

RECOMMENDATIONS Adults: Chew one tablet once or twice daily, or as directed by a healthcare practitioner. Children: As directed by a healthcare practitioner.

PRECAUTIONS The safety of CoQ10 has been evaluated. Dosages in studies have ranged from 100 mg every day to 1200 mg per day. To date, no toxicities have been reported. Occasional gastric upset may occur.12,13 Taking Smart Q10™ CoQ10 wafers with meals usually alleviates this rare upset.1

The products and the claims made about specific products on or through this site have not been evaluated by The House of Nutrition Online or the United States Food and Drug Administration and are not approved to diagnose, treat, cure or prevent disease. The information provided on this site is for informational purposes only and is not intended as a substitute for advice from your physician or other health care professional or any information contained on or in any product label or packaging. You should not use the information on this site for diagnosis or treatment of any health problem or for prescription of any medication or other treatment. You should consult with a healthcare professional before starting any diet, exercise or supplementation program, before taking any medication, or if you have or suspect you might have a health problem.
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