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Description
For nearly 2800 years the Chinese have used extracts from the Ginkgo biloba tree to treat a variety of conditions to maintain the healthy normal function of the brain, cardiovascular, blood and blood vessels, circulatory, and metabolic processes. Ginkgo may:
Help to maintain normal circulation
Help to maintain the normal function and tone of blood vessels
Maintain oxygen and glucose metabolism in the brain
Prevent capillary fragility and blood leakage into surrounding tissue
Help the normal function of factors that maintain a normal blood flow
Maintain normal coagulation of blood
Reduce tissue damage caused by low blood flow
May help control radiation-induced brain edema in-vitro
Help slow the aging process in the brain
Ginkgo contains numerous antioxidants such as the proanthocyanidins and flavonoids, which counteract free-radical activity. Flavonoids are also known to strengthen capillaries, which can promote healthy blood flow to the brain, helping to maintain cognitive health.
People often associate ginkgo with healthy cognitive function, but a review of hundreds of published studies reveals that this flavonoid probably benefits every cell in the body. In addition to maintaining healthy arterial function116 via several well-defined mechanisms, ginkgo also functions as a platelet aggregation inhibitor.
Ginkgo biloba acts similar to a potent antioxidant and scavenger of most free radical species, such as hydroxyl and peroxyl radicals and superoxide anions. It is known to protect the energy-producing mitochondria in the cells, thus enhancing oxygen utilization and cellular respiration.
Life Extension's Ginkgo Biloba Certified Extract contains 24% ginkgo flavone glycosides and 6% terpene lactones. In addition to what is certified to be in the product, what is not in this extract is also important. The health regulatory agency that regulates ginkgo purity in Germany mandates that it not contain more than 5 ppm of ginkgolic acid. Life Extension's low-cost ginkgo contains less than 1 ppm of this toxic part of the ginkgo leaf.
References Ginkgo biloba extract is a potent antioxidant and scavenger of most free radical species, such as hydroxyl and peroxyl radicals and superoxide anions.38 It is known to protect the energy -producing mitochondria within the cells, thus enhancing oxygen utilization and cellular respiration.
In a study to determine whether ginkgo extract could prevent age-associated cellular changes, the brain and liver mitochondria of old mice fed ginkgo extract in their drinking water was compared to those of young and old control mice. Mitochondria from the rats given ginkgo exhibited significantly less genetic damage, peroxide generation, and oxidation of the crucial antioxidant glutathione than the nonsupplemented rats. In addition, mitochondria from the old rats given the ginkgo extract resembled those of the young rats much more closely, being similar in size and morphology. The study concluded that standardized ginkgo extract prevents age-related decline in mitochondrial structure and function by protecting mitochondria from oxidative damage.
The pharmaceutical grade botanical extract in Ginkgo Biloba Certified Extract has been concentrated and dual standardized to ensure the highest quality, consistency, and biological activity. The phytonutrient profile of Ginkgo Biloba Certified Extract is comparable to the Gbe 24/6 extract used in clinical studies worldwide and monographed in German Commission E. The health regulatory agency that regulates ginkgo purity in Germany mandates that ginkgo not contain more than 5 ppm of ginkgolic acid. Ginkgo Biloba Certified ExtractTM contains less than 1 ppm of this toxic part of the ginkgo leaf. Ginkgolic acid is a substance related to anacardic acid (poison ivy) and may cause an allergic reaction in some people. Ginkgo Biloba Certified Extract has the lowest ginkgolic acid level available.
Ginkgo Biloba Certified Extract has high levels of ginkgolide B (>0.8%), which is the most studied terpene lactone, and thought to be a potent inhibitor of platelet activating factor (PAF). PAF is a powerful inflammatory mediator.
Suggested Use
Take one capsule per day, or as directed by a healthcare practitioner. This product is best utilized when taken with food.
Supplement Facts
Supplement Facts
Serving Size 1 Capsule
Amount Per Serving % Daily Value
Ginkgo Biloba (leaf) Extract (Standardized for 24% Ginkgoflavonglycosides {28.8 mg}, 6% total Terpene Lactones {7.2 mg}, and <1ppm Ginkgolic Acid) 120 mg †
† Daily Value not established.
** Percent Daily Values are based on a 2,000 calorie diet.
Other Ingredients
Rice flour, gelatin, magnesium stearate.
Warnings
Caution: Do not take more than 120 mg a day of ginkgo. If you are taking anticoagulants or MAO inhibitors, consult your doctor before taking ginkgo. Not for use by pregnant or lactating women. The pharmaceutical grade botanical extract in Ginkgo Biloba Certified Extract has been concentrated and dual standardized to ensure the highest quality, consistency, and biological activity. Ginkgo Biloba Certified Extract contains the lowest level of ginkgolic acid available, even lower than the stringent 5 ppm German Commission E limit. Ginkgolic acid is an allergen for some people and is present in much higher levels in lower quality products.
Keep out of reach of children. Do not exceed recommended dose. Do not purchase if outer seal is broken or damaged. If you have a bad reaction to product discontinue use immediately. When using nutritional supplements please inform your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
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