What is Manganese?
Manganese is a mineral found in large quantities in both plant and animal matter. Only trace amounts of this element can be found in human tissue. Manganese is predominantly stored in the bones, liver, kidney, and pancreas. It aids in the formation of connective tissue, bones, blood-clotting factors, and sex hormones and plays a role in fat and carbohydrate metabolism, calcium absorption, and blood sugar regulation. Manganese is also necessary for normal brain and nerve function.
Health Benefits and Usage:
Manganase enables the body to utilize vitamin C, B1, biotin as well as choline. It is used in the manufacture of fat, sex hormones and breast milk in females. It is thought to also help neutralize free radicals as well as being of assistance in preventing diabetes and needed for normal nerve function. Manganese is also indicated in stimulating growth of the connective tissue and is also thought to be of importance in brain functioning.
Manganese & Antioxidants:
Manganese is a component of the antioxidant enzyme manganese superoxide dismutase (MnSOD). Antioxidants scavenge damaging particles in the body known as free radicals. These particles occur naturally in the body but can damage cell membranes, interact with genetic material, and possibly contribute to the aging process as well as the development of a number of health conditions. Antioxidants such as MnSOD can neutralize free radicals and may reduce or even help prevent some of the damage they cause.
Low levels of manganese in the body can contribute to infertility, bone malformation, weakness, and seizures. Manganese deficiencies are considered rare, however, since it is relatively easy to obtain adequate amounts of manganese through the diet.
Interestingly, though, some experts estimate that as many as 37 of Americans do not get the recommended daily amounts of manganese in their diet. This may be due to the fact that whole grains are a major source of dietary manganese, and many Americans consume refined grains more often than whole grains. Refined grains provide half the amount of manganese as whole grains.
Apart from its uses in rare overt deficiency disorders, manganese might be helpful for those with osteoporosis and osteoarthritis as well as individuals with premenstrual syndrome (PMS). However, evidence substantiating these benefits is inconclusive.
Manganese supplementation, in combination with calcium, zinc, and copper, has shown some efficacy in postmenopausal osteoporosis. Manganese ascorbate, in combination with glucosamine hydrochloride and chondroitin sulfate, was helpful when used in connection with knee osteoarthritis pain in a recent randomized double-blind placebo-controlled pilot study.
Follow up on these studies is needed. Similarly, there is an isolated study needing follow up that suggested some possible benefit from manganese in alleviating some PMS symptoms including anxiety, depression, irritability, and mood swings.
Although the study of this mineral is still considered far from complete, manganese have been shown to be one of the most important minerals in human pathology.
Dosage and Administration:
There are several forms of supplementary manganese including manganese gluconate, manganese sulfate, manganese ascorbate, and manganese amino acid chelates. Manganese is available as a stand-alone supplement and also in combination products. One combination product used for bone/joint health contains chondroitin sulfate, glucosamine hydrochloride, and manganese ascorbate.
Typical supplemental intake of manganese ranges from 2 to 5 milligrams daily.
Manganese is one of the least toxic minerals and no RDA suggestion has been set. 2-5 mg is considered to be adequate for normal healthy adults. However, doses up to 10mg daily is still considered to be safe because the body simply doesn't absorb the mineral;. Four slices of wholemeal bread is already enough for your daily manganese supply.
Solgar's Chelated Manganese